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Congenicity across multiple generations of backcrossing R6/2 mice to C57BL/6J.

By Randi-Michelle Cowin (338113), Nghiem Bui (338114), Deanna Graham (338115), Jennie R. Green (338116), Stephan Grueninger (338117), Lisa A. Yuva-Paylor (256237), Arsalan U. Syed (338118), Andreas Weiss (135692) and Richard Paylor (256245)


<p>Average percentage of homozygous B6 markers based on the 96-marker panel. Average percent B6 homozygosity was less than 50% after the first backcross but reached congenicity of 95% by the N4 generation.</p

Topics: Genetics, Molecular Biology, Neuroscience, Biotechnology, generations, backcrossing, mice
Year: 2013
DOI identifier: 10.1371/journal.pone.0028409.g001
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Provided by: FigShare
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