Congenicity across multiple generations of backcrossing R6/2 mice to C57BL/6J.

Randi-Michelle Cowin (338113); Nghiem Bui (338114); Deanna Graham (338115); Jennie R. Green (338116); Stephan Grueninger (338117); Lisa A. Yuva-Paylor (256237); Arsalan U. Syed (338118); Andreas Weiss (135692); Richard Paylor (256245)

doi:10.1371/journal.pone.0028409.g001

Congenicity across multiple generations of backcrossing R6/2 mice to C57BL/6J.

By Randi-Michelle Cowin (338113), Nghiem Bui (338114), Deanna Graham (338115), Jennie R. Green (338116), Stephan Grueninger (338117), Lisa A. Yuva-Paylor (256237), Arsalan U. Syed (338118), Andreas Weiss (135692) and Richard Paylor (256245)

Abstract

<p>Average percentage of homozygous B6 markers based on the 96-marker panel. Average percent B6 homozygosity was less than 50% after the first backcross but reached congenicity of 95% by the N4 generation.</p

Topics: Genetics, Molecular Biology, Neuroscience, Biotechnology, generations, backcrossing, mice

Year: 2013

DOI identifier: 10.1371/journal.pone.0028409.g001

OAI identifier: oai:figshare.com:article/376123

Provided by: FigShare

Download PDF:
_{Sorry, we are unable to provide the full text but you may find it at the
following location(s):}

https://figshare.com/articles/... (external link)

Congenicity across multiple generations of backcrossing R6/2 mice to C57BL/6J.

Abstract

Suggested articles