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Ab reactivities against the MAP3865c protein are inhibited by MAP3865c<sub>125–133</sub> and MAP3865c<sub>133–141</sub> peptides.

By Speranza Masala (341013), Daniela Paccagnini (341014), Davide Cossu (341015), Vedran Brezar (337452), Adolfo Pacifico (341016), Niyaz Ahmed (20828), Roberto Mallone (337459) and Leonardo A. Sechi (84079)


<p>Ab+ and Ab-negative sera from T1D patients were pre-incubated overnight with saturating concentrations (5.5 µM) of MAP3865c<sub>125–133</sub>, MAP3865c<sub>133–141</sub>, the two peptides in combination, MAP3865c-MBP fusion protein and control or no peptide. Their reactivity on MAP3865c-MBP-coated ELISA plates was subsequently tested. Bars depict means ± SEM of triplicate wells and results are representative of three separate experiments.</p

Topics: Physiology, Chemistry, Immunology, Infectious Diseases, reactivities, map3865c, inhibited
Year: 2013
DOI identifier: 10.1371/journal.pone.0026931.g004
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Provided by: FigShare
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