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Validation of dysregulated miRNAs in sporadic versus familial papillary thyroid cancer by quantitative RT-PCR.

By Yin Xiong (342546), Lisa Zhang (339757), Alisha K. Holloway (222884), Xiaolin Wu (1682056), Ling Su (342547) and Electron Kebebew (339759)

Abstract

<p>MiR-20a was 4-fold and miR-886-3p was 3-fold higher in familial papillary thyroid cancer as compared to sporadic (p = 0.025 for miR-20a, p = 0.028 for miR-886-3p, p = 0.37 for miR-195, p = 0.46 for miR-29c). Values are average expression plus and minus the standard error of mean. The Y axis represents the ratio of miRNA and U6 RNA using 2<sup>−ΔΔCt</sup> method, and the lowest value of the sample was set to 1.0.</p

Topics: Biological Sciences, Cancer, dysregulated, mirnas, sporadic, familial, papillary, thyroid, cancer, quantitative
Year: 2013
DOI identifier: 10.1371/journal.pone.0024717.g002
OAI identifier: oai:figshare.com:article/397610
Provided by: FigShare
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