Article thumbnail

DC TLR ligand responsiveness.

By Nicole L. Yonkers (345124), Benigno Rodriguez (89118), Robert Asaad (345125), Michael M. Lederman (89120) and Donald D. Anthony (345126)

Abstract

<p><b>Panels </b><b><i>A and B</i></b>. CD86 MFI and HLA-DR MFI on isolated MDC following overnight culture in presence of Medium and poly I∶C stimulation in healthy control (n = 21) and HIV+ subjects (n = 18). The p value in panel B is for comparison between the delta HLA-DR MFI for controls and HIV infected subjects . IL-6 production from isolated MDC on a subset of the same subjects (n = 18 control and n = 16 HIV+) (<b>panel </b><b><i>C</i></b>) following overnight culture in absence and presence of poly I∶C stimulation. IL-6 production from isolated PDC on a subset of the same subjects (n = 17 control and n = 17 HIV+) (<b>panel </b><b><i>D</i></b>) following overnight culture in absence and presence of R848 stimulation. Healthy control (n = 17) and HIV+ subject (n = 16) PDC IFN-α production in response to overnight R848 stimulation is shown in <b>panel </b><b><i>E</i></b>. <b>Panel .</b> Association between MDC spontaneous IL-6 production and HIV plasma level.</p

Topics: Immunology, Infectious Diseases, tlr, ligand
Year: 2013
DOI identifier: 10.1371/journal.pone.0023884.g002
OAI identifier: oai:figshare.com:article/410481
Provided by: FigShare
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://figshare.com/articles/... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.