<p>(A) Chemical structures of rhizoxin, an antimitotic macrolide, and rhizonin A, a hepatotoxic cyclopeptide. (B) Light micrograph of a sporangium of <i>R. microsporus</i> (ATCC 62147) stained with a viability assay system (Invitrogen). Green spots are living cells of the bacterial endosymbiont <i>B. rhizoxinica</i>. (C) Life cycle of <i>R. microsporus</i> strains and their endosymbionts <i>B. rhizoxinica</i> and <i>B. endofungorum</i>. Endobacteria are propagated within fungal spores (vertical transmission). Under laboratory conditions, isolated bacteria can infect compatible host strains (horizontal transmission).</p
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