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1-D-MT does not inhibit the proliferation or cell cycle progression of SKOV-3 cells.

By Christiane A. Opitz (351069), Ulrike M. Litzenburger (126790), Uta Opitz (351071), Felix Sahm (126791), Katharina Ochs (351073), Christian Lutz (351075), Wolfgang Wick (126794) and Michael Platten (34815)


<p>(<b>A</b>) <sup>3</sup>[H] methylthymidine incorporation of SKOV-3 cells treated with 1 mM 1-D-MT (black bar) or vehicle (white bar) for 6 days. (<b>B</b>) Cell cycle analysis of SKOV-3 cells treated with 1 mM 1-D-MT or vehicle for 48 h. (<b>C</b>) Proliferation analysis of CFSE-stained lymphocytes from 6 day cocultures of MLR with 2000 SKOV-3 cells, treated with indicated concentrations of 1-D-MT (upper panel). Plot of the cell numbers in each generation of the above experiment (lower panel).</p

Topics: Biochemistry, Molecular Biology, Pharmacology, Chemistry, Immunology, Cancer, inhibit, proliferation, progression, skov-3
Year: 2013
DOI identifier: 10.1371/journal.pone.0019823.g003
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Provided by: FigShare
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