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Lack of PDF and CRY signaling causes arrhythmic behavior under DD.

By Seol Hee Im (352293), Weihua Li (144468) and Paul H. Taghert (43433)

Abstract

<p>Group averaged actograms of each genotype under constant darkness (DD) following LD cycles. (A) <i>w<sup>1118</sup></i> flies; (B) <i>pdfr<sup>5304</sup></i> single mutant flies; (C) <i>pdfr<sup>5304</sup>; ; cry<sup>b/01</sup></i> double mutant flies; (D) <i>cry-G4<sup>(19)</sup></i>; <i>cry<sup>b</sup> ss Pdf<sup>01</sup></i>double mutant flies. The double mutant flies fail to maintain free running rhythms. For the experiment shown here, the numbers of animals averaged are 16 (A), 15 (B), 29 (C), and 24 (D).</p

Topics: Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, pdf, signaling, causes, arrhythmic
Year: 2013
DOI identifier: 10.1371/journal.pone.0018974.g002
OAI identifier: oai:figshare.com:article/448809
Provided by: FigShare
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