Pluripotency in the WT and <i>Prnp</i>-null cell lines.
<p>WT EB mRNA (<b>A</b>) and KO EB mRNA (<b>B</b>) expression patterns of three pluripotency genes during differentiation. Note the lack in the KO line (<b>B</b>) of an increase in <i>Nanog</i> expression on Day 5. C) WT EB mRNA expression pattern of <i>Prnp</i> during differentiation (Days 0, 1, 2, 3, 5, 7 and 13). <i>Prnp</i> is expressed at its highest levels on Day 5 (Error bars, s.e.m.).</p
Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, wt
DOI identifier: 10.1371/journal.pone.0018422.g002
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