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Cellular immune responses.

By Jae-Min Song (329011), Bao-Zhong Wang (329013), Kyoung-Mi Park (329009), Nico Van Rooijen (40828), Fu-Shi Quan (329010), Min-Chul Kim (329007), Hyun-Tak Jin (357487), Andrew Pekosz (357488), Richard W. Compans (111751) and Sang-Moo Kang (329015)

Abstract

<p>The cellular immune responses were assessed with splenocytes isolated from mice 4 weeks boost immunization with M2 VLPs or M1 only VLPs without M2 (Mock) before challenge (A–C) and at 4 day post challenge (D–F) with A/Philippines/82 virus (n = 6). Cells from spleen (A, D), lung (B, E), and BAL (C, F) were stimulated with M2 peptides for 2 days and cytokine forming cell spots were determined by ELISPOT assay. The asterisk indicates a significant difference between M2VLP and Mock groups, * p<0.05, ** p<0.01.</p

Topics: Immunology, Infectious Diseases, immunology/immune response, virology/host antiviral responses, virology/vaccines
Year: 2013
DOI identifier: 10.1371/journal.pone.0014538.g005
OAI identifier: oai:figshare.com:article/476440
Provided by: FigShare
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