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1, 9 PA enhances HIF-1α ubiquitination.

By Yang Lu (59885), Xinqun Li (59884), Haiquan Lu (358224) and Zhen Fan (59888)

Abstract

<p>(A). A431 cells were treated with 10 µM 1, 9 PA for indicated time period. Cell lysates were prepared for HIF-1α immunoprecipitation, followed by Western blotting of the immunoprecipitates with antibodies directed against ubiquitin (top), HIF-1α, and β-actin. (B) A431 cells were untreated or treated with 10 µM 1, 9 PA in the presence of 10 µM MG132 for 1 h in 0.5% FBS medium. HIF-1α was immunoprecipitated followed by Western blot analysis with an anti-HIF-1α antibody.</p

Topics: Biochemistry, Molecular Biology, Physiology, Pharmacology, Cancer, pa, enhances
Year: 2013
DOI identifier: 10.1371/journal.pone.0015823.g004
OAI identifier: oai:figshare.com:article/479909
Provided by: FigShare
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