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The TCRα LCR drives significant mRNA expression levels of a 3′-linked HLA-B7 reporter gene in B cells.

By Stefan Knirr (359521), Janette Gomos-Klein (359523), Blanca E. Andino (359524), Faith Harrow (359525), Karl F. Erhard (359526), Damian Kovalovsky (254810), Derek B. Sant'Angelo (254823) and Benjamin D. Ortiz (254816)

Abstract

<p>(<b>A</b>) Northern blot analyses of RNA prepared from thymocytes and isolated spleen B cells from three independent lines of 1:8-B7 transgenic mice. Thy  =  Thymus, SpB  =  Spleen B cells, NTG  =  non-transgenic. (<b>B</b>) Graph depicting PhosporImager analyses of HLA-B7 reporter expression levels normalized to 18S rRNA. Y-axis values are expressed relative to thymus mRNA levels (designated as 100%).</p

Topics: Genetics, Molecular Biology, Biotechnology, Immunology, Developmental Biology, lcr, drives, mrna, levels, hla-b7
Year: 2013
DOI identifier: 10.1371/journal.pone.0015527.g005
OAI identifier: oai:figshare.com:article/487384
Provided by: FigShare
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