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Comparison BFS-method vs. HiNO using the TRN of S. cerevisiae.

By Mara L. Hartsperger (165058), Robert Strache (360052) and Volker Stümpflen (13745)

Abstract

<p>A snapshot of the results (the comparison of the BFS-approach and HiNO) using the TRN of S. cerevisiae is shown. Node colors indicate the level assignment in HiNO: blue - level 1; green - level 2; red - level 3; yellow - level 4. Dashed edges represent additional regulatory interdependencies (further up- and/or down-stream factors) that are not shown. The results of the BFS method are shown in (<b>A</b>). The node coloring indicates conflicts in level assignment. In (<b>B</b>) the result of the “downgrade” step of HiNO is shown. In (<b>C</b>) the result of the “upgrade” step is shown. This is also the final hierarchical assignment of the elements by HiNO.</p

Topics: Biochemistry, Medicine, Biological Sciences, Cancer, Computational Biology, bfs-method, hino, trn
Year: 2013
DOI identifier: 10.1371/journal.pone.0013698.g007
OAI identifier: oai:figshare.com:article/491331
Provided by: FigShare
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