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Contribution of S100A8/A9 to cytokine and chemokine production during UTI.

By Mark C. Dessing (360919), Loes M. Butter (313736), Gwendoline J. Teske (360920), Nike Claessen (29069), Chris M. van der Loos (33615), Thomas Vogl (125044), Johannes Roth (125060), Tom van der Poll (33907), Sandrine Florquin (29075) and Jaklien C. Leemans (313737)

Abstract

<p>Chemokine and cytokine levels (KC, MIP-2 and TNF-α) in bladder (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013394#pone-0013394-g004" target="_blank">figure 4A–C</a>) and kidney (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013394#pone-0013394-g004" target="_blank">figure 4D–F</a>) homogenates from WT mice (black squares) and S100A9 KO mice (white squares), 24 and 48 hours after inoculation with 4.5×10<sup>8</sup> or 9.0×10<sup>8</sup> CFU <i>E. coli</i>/mouse. Sham mice were sacrificed 24 hours after inoculation with sterile PBS. Single experimental data are mean ± SEM. N = 6–9 mice per group, *P<0.05 vs. WT mice.</p

Topics: Medicine, Immunology, Infectious Diseases, cytokine, chemokine
Year: 2013
DOI identifier: 10.1371/journal.pone.0013394.g004
OAI identifier: oai:figshare.com:article/495420
Provided by: FigShare
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