This paper presents a review on recent developments of one-dimensional (1-D) nanostructures based label-free chemiresistive/chemFET biosensors and the various sensing mechanisms used for biomolecular detection. The sensor performance including sensitivity, selectivity, and reliability is compared in terms of material synthesis of the sensor's element, relating surface functionalization schemes to their properties with respect to selected bioreceptors, its method of fabrication, and its intended operation. As a final point, we outline the prospects of chemiresistive/chemFET biosensors and recommend specific advancements in this field. (C) 2014 Elsevier B.V. All rights reserved.We acknowledge the financial support by KIMS Academy Laboratory from Korea Institute of Materials Science and the Brianpool Program
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