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<i>HLA-A</i>, <i>-B</i> and -C allele frequencies in the Ga-Adangbe.

By Paul J. Norman (234033), Jill A. Hollenbach (122557), Neda Nemat-Gorgani (478412), Lisbeth A. Guethlein (122560), Hugo G. Hilton (478413), Marcelo J. Pando (478414), Kwadwo A. Koram (172174), Eleanor M. Riley (25407), Laurent Abi-Rached (234028) and Peter Parham (179940)

Abstract

<p>Shown are the HLA-A, -B and -C allotypes (left) identified in the Ga-Adangbe study population (2N = 366), their frequencies (centre) and the KIR they interact with (right); † – from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003938#pgen.1003938-Graef1" target="_blank">[113]</a> and Hilton <i>et al.</i> (unpublished). Characteristic alleles of sub-Saharan African populations <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003938#pgen.1003938-Solberg1" target="_blank">[13]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003938#pgen.1003938-GonzalezGalarza1" target="_blank">[74]</a> are shown in bold. By frequency, approximately half of the <i>HLA-A</i> and <i>-B</i> and one third of the HLA-C alleles are specific to sub-Saharan Africans (twelve <i>HLA-A</i> alleles; combined frequency 50.3%: fourteen <i>HLA-B</i> alleles; and 45.4%: three <i>HLA-C</i> alleles; 32.8%).</p

Topics: Earth and Environmental Sciences, Ecology, Biological Sciences, -c, allele, frequencies
Year: 2013
DOI identifier: 10.1371/journal.pgen.1003938.g005
OAI identifier: oai:figshare.com:article/838434
Provided by: FigShare
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