Interaction of βig-h3 with integrin α2β1 mediates metastasis of human osteosarcoma cells.
Abstract
<p>The amounts of cell adhesion (A), invasion (B) and migration (C) were tested in control siRNA or βig-h3 siRNA transfected Saos-2 cells which were incubated with P1E6 and 6S6, alone or combination. Scale = 100 µm. Bars represent the mean of triplicate samples; error bars represent standard deviation. Data are representative of three independent experiments. *P<0.05 by one-way ANOVA analysis.</p- Image
- Figure
- Medicine
- Biological Sciences
- Biochemistry
- Biomacromolecule-ligand interactions
- Molecular cell biology
- Extracellular matrix
- integrins
- Signal transduction
- Signaling pathways
- cell adhesion
- oncology
- Basic cancer research
- metastasis
- Cancers and neoplasms
- Bone and soft tissue sarcomas
- osteosarcoma
- Cancer risk factors
- Cancer treatment
- pediatrics
- Public health
- Child health
- integrin
- mediates
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This paper was published in FigShare.
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