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Interaction of βig-h3 with integrin α2β1 mediates metastasis of human osteosarcoma cells.

By Yun-Shan Guo (530568), Rui Zhao (43391), Jie Ma (166937), Wei Cui (92129), Zhen Sun (269397), Bo Gao (106513), Shu He (530569), Yue-Hu Han (530570), Jing Fan (149601), Liu Yang (23752), Juan Tang (437969) and Zhuo-Jing Luo (316583)

Abstract

<p>The amounts of cell adhesion (A), invasion (B) and migration (C) were tested in control siRNA or βig-h3 siRNA transfected Saos-2 cells which were incubated with P1E6 and 6S6, alone or combination. Scale = 100 µm. Bars represent the mean of triplicate samples; error bars represent standard deviation. Data are representative of three independent experiments. *P<0.05 by one-way ANOVA analysis.</p

Topics: Medicine, Biological Sciences, Biochemistry, Biomacromolecule-ligand interactions, Molecular cell biology, Extracellular matrix, integrins, Signal transduction, Signaling pathways, cell adhesion, oncology, Basic cancer research, metastasis, Cancers and neoplasms, Bone and soft tissue sarcomas, osteosarcoma, Cancer risk factors, Cancer treatment, pediatrics, Public health, Child health, integrin, mediates
Year: 2014
DOI identifier: 10.1371/journal.pone.0090220.g004
OAI identifier: oai:figshare.com:article/951738
Provided by: FigShare
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