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Multivariate analysis using PCA of the parameters in tables 1 and 2 (with BMI and age excluded) using two significant principal components based on eigenvalue criteria (>2).

By Anna Wuolikainen (225730), Jure Acimovic (430166), Anita Lövgren-Sandblom (430167), Paolo Parini (87438), Peter M. Andersen (172248) and Ingemar Björkhem (430172)

Abstract

<p>A. Females with ALS overlapped with female controls in the measured parameters. (t <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113619#pone.0113619-Andersen1" target="_blank">[1]</a>, 34% of variation vs. t <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113619#pone.0113619-Desport1" target="_blank">[2]</a>, 20% of variation; R2 = 0.67; Q2 = .25). B) The male ALS group was shifted from the male controls in the measured parameters. (t <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113619#pone.0113619-Andersen1" target="_blank">[1]</a>, 36% of variation vs. t <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113619#pone.0113619-Desport1" target="_blank">[2]</a>, 15% of variation; R2 = 0.51; Q2 = 0.22).</p

Topics: Uncategorised, coenzyme Q, density lipoprotein cholesterol, cyp, SOD 1. Plasma levels, Coenzyme Q Homeostasis, 52 ALS patients, Lipid profiles, survival, 40 control subjects, hydroxycholesterol, 27a, Pathogenic Factor High plasma levels
Year: 2014
DOI identifier: 10.1371/journal.pone.0113619.g001
OAI identifier: oai:figshare.com:article/1249559
Provided by: FigShare
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