miR26b* and miR562 overexpression in MCF7 cells enhances endothelial cell angiogenesis while silencing miR26b* and miR562 inhibits angiogenesis.
<p>MCF7 cells were transfected with empty vector (EV), miR26b* or miR562 and a co-culture using transwells was performed with HUVEC in matrigel. (A,C) Average number of tubes formed per field of view and (B,D) average tube length was analyzed. Similar co-culture experiments were performed with MCF7 cells silenced with control, anti-miR26b* and anti-miR562. (D,G) Average number of tubes formed per field of view and (F,H) average tube length was analyzed. * p<0.05 ** p<0.01 vs control cells.</p
Biological Sciences, miR 26b, 2 novel miRNAs, MCF 7 breast cancer cells, ANXA 1, cell tube formation, miR 562, MCF 7 cells, tube formation, nf, Breast Cancer Cells Annexin 1, breast cancer metastasis, utr, wound healing, tnf
DOI identifier: 10.1371/journal.pone.0114507.g006
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