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Indole Alkaloid Glycosides from the Aerial Parts of <i>Strobilanthes cusia</i>

By Wei Gu (26249), Yu Zhang (12946), Xiao-Jiang Hao (693964), Fu-Mei Yang (1698892), Qian-Yun Sun (1698889), Susan L. Morris-Natschke (589662), Kuo-Hsiung Lee (113297), Yue-Hu Wang (1698886) and Chun-Lin Long (1698883)


Three indole alkaloid glycosides, strobilanthosides A–C (<b>1</b>–<b>3</b>), two known indole alkaloid glucosides (<b>4</b> and <b>5</b>), and five phenylethanoid glycosides (<b>8</b>–<b>10</b>) were isolated from the aerial parts of <i>Strobilanthes cusia</i>. The structures of the new compounds were elucidated by spectrometric analysis, and the absolute configurations of <b>1</b> and <b>2</b> were established by ECD spectrocsopy. <i>N</i>′-β-d-Glucopyranosylindirubin (<b>5</b>) showed weak antibacterial activity (MIC 62.5–125 μM) against <i>Staphylococcus aureus</i>

Topics: Biochemistry, Microbiology, Genetics, Ecology, Cancer, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Strobilanthes cusiaThree indole alkaloid glycosides, glucoside, MIC, compound, phenylethanoid, Indole Alkaloid Glycosides, Aerial Parts, Staphylococcus aureus, Strobilanthes cusia, ECD spectrocsopy, strobilanthoside, configuration, analysis
Year: 2014
DOI identifier: 10.1021/np5003274.s001
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Provided by: FigShare
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