Interleukin-1 receptor signaling controls MyD88-dependent chemokine induction and neutrophil recruitment.


<p>Mean (+SEM) of (A, C) BALF, (B, D) lung neutrophil recruitment and (E, G, I) BALF and (F, H, J) lung, (E, F) CXCL1, (G, H) CXCL2 and (I, J) CXCL5 levels in WT (black bars), IL-1R<sup>(−/−)</sup> (bars with diagonal stripes), IL-18R<sup>(−/−)</sup> (bars with crosshatch), TLR2<sup>(−/−)</sup> (dark grey bars), and TLR4<sup>(−/−)</sup> (light grey bars) mice 10 h p.i. with 3 × 10<sup>7</sup> conidia. Data are from 2 (A-D) or 1 (E-J) experiment(s) with 5–7 mice per genotype in each experiment. Graphs from a single experiment (out of three independent experiments) are shown for E, G and I.</p

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oaioai:figshare.com:article/1295088Last time updated on 2/12/2018

This paper was published in FigShare.

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