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Effect of NNK and beta-adrenoceptors on cell migration and invasion.

By Nana Zhang (500518), Xiujing Sun (443934), Mingjiong Sun (699927), Shengtao Zhu (470078), Li Wang (15202), Dan Ma (699928), Yongjun Wang (134570), Shutian Zhang (470080) and Peng Li (69518)

Abstract

<p>Variously treated KYSE410 cells were seeded in Boyden chambers for migration or invasion assays. At the end of the experiments, migratory or invasive cells that were on the bottom surface were fixed, stained with hematoxylin and eosin, and then counted under a microscope at 200×. Data were obtained from three independent experiments. <sup>ε</sup> p<0.05 compared with the blank group; <sup>ζ</sup> p<0.05 compared with the negative group; <sup>ξ</sup> p<0.05 compared with the negative+NNK group. Negative is representative of nonspecific control siRNA for beta-adrenoceptors.</p

Topics: Biological Sciences, ESCC cell migration, cell carcinoma, nnk, oncogenic effects, rescue effect, xenograft tumor growth, growth factor, oncogenic role, vivo results, Vivo Cigarette smoke, oncogenic features, therapy strategy, risk factor, erk, beta, Protein expression, ESCC cell proliferation
Year: 2015
DOI identifier: 10.1371/journal.pone.0118845.g004
OAI identifier: oai:figshare.com:article/1329682
Provided by: FigShare
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