Neutrophil recruitment following <i>L</i>. <i>braziliensis</i> inoculation.
Abstract
<p>Individual BALB/c mice were injected with <i>L</i>. <i>braziliensis</i> in the ear dermis. At different time points, cells were prepared and stained for Ly6G and analyzed by flow cytometry. (A) Representative dot plots and gating strategy of neutrophils. (B) Bar graph representation of the number of Ly6G<sup>+</sup> cells in naïve mice (grey bars), in mice inoculated with saline (white bars) or inoculated with <i>L</i>. <i>braziliensis</i> (black bars). Data shown (mean ± SEM) are from one experiment representative of two. ***p <0.001, *p<0.05.</p- Image
- Figure
- Biological Sciences
- parasite load
- neutrophil recruitment
- neutrophil accumulation
- parasite elimination
- Cell activation
- braziliensis promastigotes
- CD 62L
- apoptotic fate.Methods
- surface molecules
- Leishmania inoculation
- apoptosis.ConclusionsWe show
- braziliensis exposure
- oxidative burst
- neutrophil elastase
- CD 18
- Leishmania braziliensis infection
- Neutrophil activation
- bystander cells
- bone marrow neutrophils
- Apoptosis BackgroundNeutrophils
- 24 h
- Leishmania braziliensis Triggers Neutrophil Activation
- tnf