<p>1) Pathogenic microbes that invade the airway 2) cause both the resident macrophages and the epithelial cells to secrete IL-8. 3) IL-8 exposure causes intracellular signaling within the epithelial cells that augments <i>de novo</i> protein synthesis and apical localization of CAR<sup>Ex8</sup>. 4) IL-8 simultaneously recruits neutrophils that transmigrate through the epithelium from the basal surface to the apical surface and 5) bind to CAR<sup>Ex8</sup> at the apical surface of the epithelium. 6) AdV entering the airway hijacks the host innate immune response and apical CAR<sup>Ex8</sup> to gain entry into the host cell.</p

Similar works

Full text



Last time updated on 12/02/2018

This paper was published in FigShare.

Having an issue?

Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.