The morphological change of mitochondria in wild type (HD1A) and <i>lal</i>-/- (HD1B) cells.

Abstract

<p>(A) MitoTracker Green FM staining of live wild type (HD1A) and <i>lal</i>-/- (HD1B) cells. Bar = 25 μm. (B) Cell proliferation of wild type (HD1A) and <i>lal</i>-/- (HD1B) cells <i>in vitro</i>; (C) Western blot analyses of protein expression of Opa1 and phosphorylation at Ser616 of DRP1 in wild type (HD1A) and <i>lal</i>-/- (HD1B) cells. (D) Concentrations of glucose, pyruvate and the aconitase activity in HD1A and HD1B cells were measured. Results are means ± SD from three independent experiments (n = 3), *, p< 0.05.</p