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The morphological change of mitochondria in wild type (HD1A) and <i>lal</i>-/- (HD1B) cells.

By Xinchun Ding (180786), Lingyan Wu (180793), Cong Yan (165323) and Hong Du (117108)

Abstract

<p>(A) MitoTracker Green FM staining of live wild type (HD1A) and <i>lal</i>-/- (HD1B) cells. Bar = 25 μm. (B) Cell proliferation of wild type (HD1A) and <i>lal</i>-/- (HD1B) cells <i>in vitro</i>; (C) Western blot analyses of protein expression of Opa1 and phosphorylation at Ser616 of DRP1 in wild type (HD1A) and <i>lal</i>-/- (HD1B) cells. (D) Concentrations of glucose, pyruvate and the aconitase activity in HD1A and HD1B cells were measured. Results are means ± SD from three independent experiments (n = 3), *, p< 0.05.</p

Topics: Biological Sciences, myeloid cell functions, ROS production, lal, HD 1B myeloid cell line, mdsc, lysosomal acid lipase, HD 1B cells, HD 1B myeloid cell lines, immunosuppress T cells, HD 1B cell ability, cancer cells proliferation, HD 1A cells, cancer cell proliferation, mTOR signal pathway
Year: 2015
DOI identifier: 10.1371/journal.pone.0121001.g003
OAI identifier: oai:figshare.com:article/1355299
Provided by: FigShare
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