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Neonatal <i>S</i>. <i>pneumoniae</i> infection enhances ovalbumin-induced airway hyperresponsiveness.

By Baohui Yang (162678), Ru Liu (713667), Ting Yang (189879), Xiaoli Jiang (418410), Liqun Zhang (115900), Lijia Wang (314011), Qinghong Wang (195082), Zhengxiu Luo (314010), Enmei Liu (314015) and Zhou Fu (314013)


<p>Whole-body plethysmography in uninfected, allergic (OVA), neonatal infected, allergic (Neo/OVA), neonatal infected, non-allergic (Neo), and uninfected, non-allergic (control) mice was conducted 24 h following challenge with methacholine. Data are reported as mean ± standard error from three separate experiments (<i>n</i> = 6–8 mice/group); *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001 <i>vs</i>. control; <sup>#</sup><i>P</i> < 0.05, <sup>###</sup><i>P</i> < 0.001 <i>vs</i>. OVA.</p

Topics: Biological Sciences, Th 17 cells, neutrophil recruitment, alleviated airway inflammation, D 39. Mice, Neonatal Streptococcus pneumoniae Infection May Aggravate Adulthood Allergic Airways Disease, adulthood hallmark features, pneumoniae infection, adulthood asthma, pneumoniae lung infection, bronchoalveolar lavage fluid, balf, Streptococcus pneumoniae infection, airway hyperresponsiveness, aad, il
Year: 2015
DOI identifier: 10.1371/journal.pone.0123010.g004
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Provided by: FigShare
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