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Confocal microscopy images showing the intracellular localization of coumarin-6-loaded PEG-PLA micelles in A549 cells.

By Zhuoyang Fan (491761), Cheng Chen (136164), Xiaoying Pang (715691), Zhou Yu (715692), Yang Qi (715693), Xinyi Chen (491760), Huihui Liang (715694), Xiaoling Fang (491763) and Xianyi Sha (491764)


<p>(a) nucleus, (b) PEG-PLA micelles, and (c) lysosomes were distinguished using Hoechst 33342 (blue), coumarin 6 (green), and Lyso Tracker Red (red). (d) Yellow represents the colocalization of Lyso Tracker Red with Green (coumarin-6-loaded PEG-PLA micelles). A, B, C, and D show the localization of coumarin-6-loaded mixed micelles.</p

Topics: Biological Sciences, MDR tumors, vitamin, PTX delivery system, micelle, vehicle
Year: 2015
DOI identifier: 10.1371/journal.pone.0120129.g008
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Provided by: FigShare
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