<p>(<b>A</b>) Growth rates of shSep15, shTR1 and shTR1/Sep15 cells compared to controls (<i>n</i> = 6). (<b>B</b>) Anchorage-independent growth in soft agar of shSep15, shTR1 and shTR1/Sep15 cells compared to controls (<i>n</i> = 4–8). (<b>C</b>) Formation of experimental lung metastases after i.v. injection of 5×10<sup>5</sup> cells (control, shSep15, shTR1, or shTR1/shSep15) into BALB/c mice (<i>n</i> = 10/construct). (<i>***P</i><0.001, compared to control).</p
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