Internalization interplay between two anti-EphA2 mAbs monitored by immunofluorescence.

Abstract

<p>Surface-bound 3035 (red color) and 1C1 (green color) were concurrently internalized in PC-3 cells for 0 or 1 hr at 37°C and processed for confocal immunofluorescence microscopy with the lysosomal marker LAMP1 (blue color). Scale bar, 45 micron. White arrows illustrate colocalization. Representative staining from one of multiple independent experiments is shown.</p