Pairwise linkage disequilibrium (LD) diagram for <i>CPT1B</i> and <i>CPT2</i> in Inuit.
<p>LD block was delineated using confidence intervals (Gabriel et al), and 0.6–0.98 for strong LD. Variants of MAF<0.05 were indicated with dashed-line. Variants were extracted from exome sequencing and SNP array data, with the asterisk indicated variants only genotyped by the SNP array. D value <1 was shown in the box, with red color indicated LOD ≥2.</p
Genetics, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Marine Biology, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, variant CPT 1A p.P 479L, Nunavik Inuit Population Background Nunavik Inuit, carnitine acyltransferase gene variations, CPT 1A, CPT 1C, Missense Mutation Burden, Nunavik Inuit, allele frequency differences, CROT, genes CPT 1A, SNP array genotyping, Metabolism Related Genes, acid metabolism genes, carnitine acyltransferases, Methods Exome sequencing, CPT 1B, CPT 2, 113 Nunavik Inuit individuals, CRAT
DOI identifier: 10.1371/journal.pone.0128255.g003
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