oai:figshare.com:article/1455153A proposed scheme of pathogenesis of HS.
Abstract
<p>Patients with HS have monocytosis but cytokine responses of inflammatory monocytes and T17 lymphocytes are inhibited. This inhibition is mediated for T17 cells by tumour necrosis factor-alpha (TNFα). When cells migrate to tissues from the blood vessels through the vascular endothelium, capacity for excess production of TNFα, interleukin (IL)-1β, IL-1α, IL-6 and IL-17 is restored.</p- Image
- Figure
- Biological Sciences
- cytokine gene copies
- cytokine profiles
- Hurley III patients
- hs
- week 8. ConclusionsFindings
- Hidradenitis Suppurativa BackgroundFavorable treatment outcomes
- 120 patients
- pbmc
- hidradenitis suppurativa
- TNF blockade
- Compartmentalized Cytokine Responses
- cytokine responses
- monocyte
- flow cytometry
- cytokine production
- Clinical improvement
- il
- measured.ResultsCD 14brightCD
- compartmentalized cytokine expression
- Isolated blood
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Provided original full text linkoai:figshare.com:article/1455153Last time updated on 2/12/2018This paper was published in FigShare.
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