Low dose JASP treatment interferes less severely with central signaling localization.


<p>(<b>A, C</b>) Representative interactions of a 5C.C7 T cell expressing LAT-GFP (A) or PKCθ-GFP (C) with 40nM Jasplakinolide (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133231#pone.0133231.s010" target="_blank">S6</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133231#pone.0133231.s011" target="_blank">S7</a> Videos) are given similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133231#pone.0133231.g001" target="_blank">Fig 1B</a>. (<b>B, D</b>) The corresponding pattern classifications are given similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133231#pone.0133231.g003" target="_blank">Fig 3C</a> (number of cell couples analyzed across multiple independent experiments, n = 44, n = 48). Control ‘any interface’ and ‘central’ accumulation curves [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133231#pone.0133231.ref003" target="_blank">3</a>] are plotted as a reference in broken lines. Error bars represent s.e.m..</p

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oai:figshare.com:article/1501229Last time updated on 2/12/2018

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