Effects of A779 on TGF-β1/Smad signaling and <i>ROS generation</i> in Ang II-stimulated rat tubular epithelial cells.


<p>NRK-52E cells were exposed to Ang II (1 μM, 16 h) with or without 1 h pretreatment with Ang-(1–7) (1 μM) and Mas receptor antagonist A779 (1 μM). (a) TGF-β1/Smad expression was analyzed. (b) The generation of reactive oxygen species (ROS) was detected using the ROS-sensitive fluorescent dye, DCF-DA. Each column represents the mean ± SEM. *<i>P</i> < 0.05. **<i>P</i> < 0.01. Data are representative of at least three independent experiments.</p

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oai:figshare.com:article/1598256Last time updated on 2/12/2018

This paper was published in FigShare.

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