Abstract

<p><i>Y</i>. <i>enterocolitica</i> serotype O:8 8081v was used to infect Caco-2 cells (MOI 10) incubated at normoxia and treated with DMOG for 7 hr. The infection was performed at normoxia. (A) The percentage of internalized bacteria was significantly reduced in DMOG treated cells. There was no significant difference in the number of associated bacteria (B) or in bacterial growth (C) in the cells between treated and untreated. (D) Treatment with DMOG did not result in significant differences in cytotoxicity. (E) Western blots of β1 integrin and HIF-1α and their (F) quantification in Caco-2 cells treated with DMOG for 7 hr as compared to untreated controls. * p ≤ 0.05; ** p ≤ 0.01 using two-tailed Student’s <i>t</i>-test.</p

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Last time updated on 12/02/2018

This paper was published in FigShare.

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