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Representative immunohistochemistry photomicrographs and quantification of subtype M1 macrophages (iNOS-positive cells).

By Fernanda Ferreira Cruz (846949), Lucas Felipe Bastos Horta (846950), Lígia de Albuquerque Maia (846951), Miquéias Lopes-Pacheco (641924), André Benedito da Silva (846952), Marcelo Marco Morales (846953), Cassiano Felippe Gonçalves-de-Albuquerque (846954), Christina Maeda Takiya (87691), Hugo Caire de Castro-Faria-Neto (846955) and Patricia Rieken Macedo Rocco (846956)


<p>(A) Lung parenchyma, C-DMSO, C-DAS, SIL-DMSO, SIL-DAS. (B) Silicotic granuloma, SIL-DMSO, SIL-DAS. Arrows: iNOS-positive cells; white bars: DMSO; gray bars: DAS. Values are means (± SD) of 6 animals per group. *Significantly different from C-DMSO group (<i>p</i> < 0.05). <sup>#</sup>DMSO <i>vs</i>. DAS (<i>p <</i> 0.05).</p

Topics: Biological Sciences, M 2 phenotype, M 2 macrophage counts, RAW 264.7 cells, M 1 macrophages, silica particles, fraction area, silicosi, macrophage cell line, macrophage polarization, dasatinib, collagen fiber content, 14 days, C 57BL mice, granuloma, tyrosine kinase inhibitor, lung mechanics, dmso
Year: 2016
DOI identifier: 10.1371/journal.pone.0147005.g005
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Provided by: FigShare
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