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Histological assessments of livers along with histo-quantification data of experimental mice in the absence (Pb-acetate) and existence of AEEF (Pb-acetate + AEEF).

By Tarun K. Dua (814888), Saikat Dewanjee (601789), Ritu Khanra (601793), Swarnalata Joardar (814891), Sujata Barma (814890), Shilpa Das (814889), M. Zia-Ul-Haq (814893) and Vincenzo De Feo (621047)


<p>Histological sections 100 x (Panel A) and 400 x (Panel B) of livers. The liver section of normal control mice showed normal portal vein and hepatocytes. Pb-acetate treated liver section exhibited dilated portal vein (green arrow), fatty degeneration (blue arrows), vacuolated cytoplasm (red arrows), apoptosis (yellow arrows) and leucocytes infiltration (black arrows) when compared with the section of normal control liver. Panel C. The dilation of portal vein is denoted as % of the blank area comparative to the whole area of the photomicrograph (400 x, arbitrarilynominated areas comprising one portal vein were selected). Panel D. The incidence of inflammation was presented as the % of the inflamed hepatocytes region comparative to the whole area of the photomicrograph (100 x, arbitrarily selected area in portal vein were designated). Values were expressed as mean ± SE, (n = 60). <sup>#</sup> Results significantly (p < 0.01)differed from normal control. <sup>**</sup>Results significantly (p < 0.01) differed from Pb-acetate control.</p

Topics: Biological Sciences, redox status, histological parameters, Hoechst staining, vivo assays, intracellular Pb burden, vivo assay, gsh, Lipid peroxidation, cytoprotective effect, ros, metal chelators, murine hepatocytes, redox systems, transcription levels, atp, Enhydra fluctuans Lour, redox balance, dna, MTT assay, mg, protein carbonylation, Pb toxicity.MethodsThe cytoprotective role, Edible Herb, Pb clearance, antioxidant effects, Acetate Intoxication BackgroundEnhydra fluctuans Lour, apoptotic proteins viz, AEEF, histological assessment, apoptotic proteins, intracellular Pb content
Year: 2016
DOI identifier: 10.1371/journal.pone.0148757.g009
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Provided by: FigShare
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