Synthesis of Ureidomuraymycidine Derivatives for Structure– Activity Relationship Studies of Muraymycins


One of the key constituents of the muraymycins is the 6-membered cyclic guanidine, (2<i>S</i>,3<i>S</i>)-muraymycidine (or <i>epi</i>-capreomycidine). In order to diversify the structure of the oligopeptide moiety of the muraymycins for thorough structure–activity relationship studies, we have developed a highly stereoselective synthesis of ureidomuraymycidine derivatives with the lactone <b>4a</b>

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oai:figshare.com:article/2529250Last time updated on 2/12/2018

This paper was published in FigShare.

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