Significant associations among correlation matrices.

Abstract

<p>Correlation matrices among cortical surface areas derived from a variety of measures are highly consistent with each other as quantified by the Mantel test coefficients with 95% confidence intervals. Each pair of bars represents two correlation methods used in the Mantel test: linear regression with errors-in-both-variables (correlation with EIV) in gray color on the left versus Pearson’s correlation in light-gray color on the right. Variables were standardized in regression analysis. *<i>p</i>≤0.05, **<i>p</i>≤0.01, ***<i>p</i>≤0.001, ****<i>p</i>≤0.0001. Twin refers to VETSA cohort, and twin-based method was used to derive genetic correlations. Genotype-based method was used to derive genetic correlations for ombined-5-cohort. The corresponding matrices are visualized in Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.g001" target="_blank">1</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.g002" target="_blank">2</a>. See also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.s002" target="_blank">S1 Fig</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.s003" target="_blank">S2 Table</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.s004" target="_blank">S3 Table</a>, and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006143#pgen.1006143.s005" target="_blank">S4 Table</a>.</p