Abstract

<p>(A) Time course of standard in vitro reaction showing radiolabeled substrate, intermediates and products of the splicing reaction. (B) Purified recombinant NS5 inhibits mature mRNA accumulation. A native or heat denature preparation of NS5 was added to the splicing reaction as indicated on the top of the gel. On the right, a graph showing dose-dependent inhibition of the splicing reaction by NS5. (C) Quantification of pre-mRNA and mature mRNA as a function of time in the presence of native NS5 or heated NS5 at 1μM.</p

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oai:figshare.com:article/3795735Last time updated on 2/12/2018

This paper was published in FigShare.

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