10.1371/journal.pone.0167063.g010

Activated microglia contact and engulf Pax6+ precursor cells.

Abstract

<p>Higher magnification of pineal gland sections immunolabeled for Iba1 (red, yellow arrows), ED1 (blue, yellow arrows) and Pax6 (green, yellow arrowheads). (A<sup>1</sup>-A<sup>6</sup>) Microglial cells with an activated morphology are enriched in cytoplasmic ED1-positive bodies and engulf Pax6<sup>high</sup> nuclei and elements. (B<sup>1</sup>-B<sup>6</sup>) Microglia with few thick projections contacting and surrounding Pax6<sup>high</sup> precursor cells. (A<sup>1</sup>-A<sup>5</sup>, B<sup>1</sup>-B<sup>5</sup>) 4x and 3.6x digital zooms from 60x images, respectively; scale bar: 5 μm. (A<sup>6</sup>, B<sup>6</sup>) 3D reconstruction of phagocytic microglia/Pax6<sup>high</sup> precursor cells or elements interactions.</p

Similar works

Full text

thumbnail-image
oai:figshare.com:article/4243010Last time updated on 2/12/2018

This paper was published in FigShare.

Having an issue?

Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.