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Decrease of viral load and ALT at different time points under treatment according to NS5A-inhibitors and interferon administration.

By Valeria Cento (103603), Thi Huyen Tram Nguyen (3776035), Domenico Di Carlo (431864), Elisa Biliotti (440233), Laura Gianserra (4033721), Ilaria Lenci (4033706), Daniele Di Paolo (152495), Vincenza Calvaruso (441341), Elisabetta Teti (4033727), Maddalena Cerrone (131618), Dante Romagnoli (4033736), Michela Melis (4033709), Elena Danieli (3801160), Barbara Menzaghi (316146), Ennio Polilli (4033712), Massimo Siciliano (4033715), Laura Ambra Nicolini (4033739), Antonio Di Biagio (316138), Carlo Federico Magni (4033733), Matteo Bolis (4033745), Francesco Paolo Antonucci (4033730), Velia Chiara Di Maio (4033718), Roberta Alfieri (79926), Loredana Sarmati (431865), Paolo Casalino (4033724), Sergio Bernardini (504056), Valeria Micheli (103632), Giuliano Rizzardini (103636), Giustino Parruti (275883), Tiziana Quirino (3162945), Massimo Puoti (182231), Sergio Babudieri (483861), Antonella D’Arminio Monforte (131628), Massimo Andreoni (103649), Antonio Craxì (114006), Mario Angelico (152517), Caterina Pasquazzi (4033742), Gloria Taliani (440231), Jeremie Guedj (140152), Carlo Federico Perno (103671) and Francesca Ceccherini-Silberstein (103660)

Abstract

<p>These graphs shows the median of predictions of ALT and HCV-RNA in different groups of treatment obtained by simulations from the parameter estimates of the two models. ALT, alanine transaminase; IFN, interferon.</p

Topics: Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, ALT decay kinetics, IFN-based regimens Background Intracellular HCV-RNA reduction, PR, ALT normalization rate, sofosbuvir, TVR, cirrhotic patients, all-DAA regimens potentiated, NS 5A, Results HCV-RNA kinetics, all-oral HCV treatment, NS 5A inhibitors, currently-used all-DAA combinations, HCV-RNA kinetics
Year: 2017
DOI identifier: 10.1371/journal.pone.0177352.g003
OAI identifier: oai:figshare.com:article/5020886
Provided by: FigShare
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