Decrease of viral load and ALT at different time points under treatment according to NS5A-inhibitors and interferon administration.
<p>These graphs shows the median of predictions of ALT and HCV-RNA in different groups of treatment obtained by simulations from the parameter estimates of the two models. ALT, alanine transaminase; IFN, interferon.</p
Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, ALT decay kinetics, IFN-based regimens Background Intracellular HCV-RNA reduction, PR, ALT normalization rate, sofosbuvir, TVR, cirrhotic patients, all-DAA regimens potentiated, NS 5A, Results HCV-RNA kinetics, all-oral HCV treatment, NS 5A inhibitors, currently-used all-DAA combinations, HCV-RNA kinetics
DOI identifier: 10.1371/journal.pone.0177352.g003
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