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Perinatally-induced hypoxic-ischemic encephalopathy? Possibilities of retrospective evaluation from the neuropediatric viewpoint

By G. Niemann, B. Vollmer and R. Goelz


This paper analyzes the feasibility of determining retrospectively, from a neuropediatric standpoint, whether an existing neurological disorder can be traced back to a perinatal hypoxic-ischemic encephalopathy. In principal, we can assume that there is a correlation between this time and pathogenesis of the brain injury on the one hand and the neurological symptoms on the other if these conditions are fulfilled 1. In the first days of live term infants revealed cerebral symptoms (like abnormality of muscle tone and consciousness and seizures) which manifest themselves in a typical sequence and are combined with involvement of other organ systems. In pre-term infants the clinical signs are often not clearly definable. 2. The subsequent neurological disorder after the primary symptoms must be a spastic-less commonly in term infants a dyskinetic one. 3. Lesions typical for the child's gestational age are visible on magnetic resonance imaging

Topics: RC0321, RJ
Year: 2005
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Provided by: e-Prints Soton
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