Article thumbnail
Location of Repository

Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis

By Sabine Pfeifer, Martin Perez-Andres, Heinz Ludwig, Surinder S. Sahota and Niklas Zojer

Abstract

An exclusive production of light chains can be found in ~15% of myeloma cases, and in these light-chain multiple myeloma (LC-MM) cases, the phenotype remains unchanged throughout subsequent progression and relapse. Once established, it suggests that this phenotype is maintained by the ‘feeder cell’ that re-populates the tumor bulk as disease re-emerges<br/><br/

Topics: QR180, RB, RC0254
Year: 2011
DOI identifier: 10.1038/leu.2011.70
OAI identifier: oai:eprints.soton.ac.uk:181785
Provided by: e-Prints Soton
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.