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Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives

By A.J. Steele, A. Al-Chalabi, K. Ferrante, M.E. Cudkowicz, R.H. Brown and J. A. Garson


These results confirm that patients with ALS have a significantly higher prevalence of serum reverse transcriptase (RT) activity than that seen in unrelated control subjects. The finding of a similarly increased prevalence in blood relatives of ALS patients raises the possibility that the observed RT activity might be due to an inherited endogenous retrovirus

Topics: RC0321
Year: 2005
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Provided by: e-Prints Soton
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