Skip to main content
Article thumbnail
Location of Repository

Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India

By Rajesh K Chudasama, Umed V Patel, Pramod B Verma, Chikitsa D Amin, Hitesh M Shah, Anupam Banerjee and Ravikant R Patel


Background: India reported first case of 2009 pandemic influenza A (H1N1) virus infection in May, 2009 and Saurashtra region in August, 2009. We describe the characteristics of fatal cases of 2009 influenza A (H1N1) infection reported in Saurashtra region. Methods: From September, 2009 to January, 2010, we observed 71 fatal cases that were infected with 2009 influenza A (H1N1) virus and admitted in different hospitals in Rajkot city. Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing was used to confirm infection; the clinico-epidemiological features were observed and documented. Results: Median age of the deceased (71) was 29 years, and 57.7% were females. Median time observed was 5 days from onset of illness to diagnosis of influenza A (H1N1), and 57.7% were referred from general practitioner (OR=0.42, CI=0.24-0.74). Median hospital stay reported was 3 days. All admitted patients received oseltamivir, but only 16.9% received it within 2 days of onset of illness. The most common symptoms were cough (97.2%), fever (93%), sore throat and shortness of breath. Co-morbid conditions were present in almost half of the patients who ultimately died, the most common of which was pregnancy (OR=0.15, CI=0.04-0.52). Radiological pneumonia was reported in 98% patients. Conclusion: Residing in urban area, delayed referral from general practitioner, presence of co-existing condition, especially pregnancy was responsible for mortality among influenza A (H1N1) infected positive

Topics: Online Journal of Health and Allied Sciences
Publisher: BS Kakkilaya
Year: 2011
OAI identifier:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • Suggested articles


    1. (2009). A preliminary analysis of the epidemiology of influenza A (H1N1) virus infection in Thailand from early outbreak data,
    2. (2009). Antigenic and genetic characteristics of swine origin
    3. (2007). Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis doi
    4. (2010). Disease Control & Prevention. FluView: a weekly influenza surveillance report prepared by the Influenza Division. Atlanta. Available from: Accessed on
    5. (2010). Disease Control & Prevention. Updated interim recommendations for the use of antiviral medications in the treatment and prevention of influenza for the 2009-2010 seasons. Atlanta. Available from: Accessed on
    6. (2009). Disease Control and Prevention (CDC). Swine influenza A (H1N1) infection in two children-Southern California, March-April
    7. (2010). Epidemiological and transmissibility analysis of influenza A (H1N1) in a southern hemisphere setting: Peru.
    8. (2010). Epidemiology of fatal cases associated with pandemic
    9. (2010). Health & Family Welfare, Government of India. Factsheet Influenza A (H1N1). Available from: Accessed on
    10. (2009). Health & Family Welfare, Government of India. Guidelines on categorization of influenza A
    11. Human swine influenza: a pandemic threat. Director General of Health Services. Government of India.
    12. Impact of influenza exposure on rates of hospital admissions and physician visits because of respiratory illness among pregnant women. doi
    13. (1998). Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. doi
    14. (2009). influenza virus infection during pregnancy in the USA.
    15. Novel swine origin influenza A (H1N1) virus investigation team. Emergence of a novel swine origin influenza A (H1N1) virus in humans.
    16. (2009). Organization. Influenza A (H1N1) – update 14.
    17. (2009). Pandemic influenza A (H1N1) in New Zealand: the experience from April to August,
    18. (2009). Profile of the first cases hospitalized due to influenza A
    19. The ANZIC influenza investigators. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. doi

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.