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Osseointegration of zirconia implants compared with titanium : an in vivo study

By Rita Depprich, Holger Zipprich, Michelle Ommerborn, Christian Naujoks, Hans-Peter Wiesmann, Sirichai Kiattavorncharoen, Hans-Christoph (Prof. Dr.) Lauer, Ulrich Meyer, Norbert Kübler and Jörg Handschel

Abstract

Background Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical surface modifications have been developed to improve osseous healing. Zirconia-based implants were introduced into dental implantology as an altenative to titanium implants. Zirconia seems to be a suitable implant material because of its tooth-like colour, its mechanical properties and its biocompatibility. As the osseointegration of zirconia implants has not been extensively investigated, the aim of this study was to compare the osseous healing of zirconia implants with titanium implants which have a roughened surface but otherwise similar implant geometries. Methods Forty-eight zirconia and titanium implants were introduced into the tibia of 12 minipigs. After 1, 4 or 12 weeks, animals were sacrificed and specimens containing the implants were examined in terms of histological and ultrastructural techniques. Results Histological results showed direct bone contact on the zirconia and titanium surfaces. Bone implant contact as measured by histomorphometry was slightly better on titanium than on zirconia surfaces. However, a statistically significant difference between the two groups was not observed. Conclusion The results demonstrated that zirconia implants with modified surfaces result in an osseointegration which is comparable with that of titanium implants

Topics: ddc:610
Year: 2008
OAI identifier: oai:publikationen.ub.uni-frankfurt.de:6527

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Citations

  1. (2000). [Clinical study of zirconium oxide bridges in the posterior segments fabricated with the DCM system]. Schweiz Monatsschr Zahnmed
  2. (2003). A: Bone response to zirconia ceramic implants: an experimental study in rabbits. J Oral Implantol
  3. (2000). Anchorage of titanium implants with different surface characteristics: an experimental study in rabbits. Clin Implant Dent Relat Res
  4. (1997). BD: Underlying mechanisms at the bone-surface interface during regeneration.
  5. (2007). Biokompatibilität und Hartgewebsintegration einphasiger oberflächenstrukturierter Zirkoniumoxidimplantate-Eine kombinierte in-vitro- und in-vivo-Studie. Implantologie
  6. (2007). Biomechanical and histomorphometric comparison between zirconia implants with varying surface textures and a titanium implant in the maxilla of miniature pigs. Clin Oral Implants Res
  7. (2003). Brach del Prever E: Alumina and zirconia ceramics in joint replacements.
  8. (1998). Comparison between freestanding and tooth-connected partially stabilized zirconia implants after two years' function in monkeys: a clinical and histologic study. J Prosthet Dent
  9. (2006). Creugers NH: Implant surface roughness and bone healing: a systematic review. J Dent Res
  10. (2005). DB: Basic reactions of osteoblasts on structured material surfaces. Eur Cell Mater
  11. (1993). Dental implants: materials and design considerations.
  12. (1996). Gu HO: Bone remodeling around implanted ceramics.
  13. (1994). Hermansson L: Effect of macrotexture produced by laser beam machining on the retention of ceramics implant in bone in vivo.
  14. (2005). Iverhed M: Bone tissue responses to surface-modified zirconia implants: A histomorphometric and removal torque study in the rabbit. Clin Implant Dent Relat Res
  15. (2002). JP: The use of reduced healing times on ITI implants with a sandblasted and acid-etched (SLA) surface: early results from clinical trials on ITI SLA implants. Clin Oral Implants Res
  16. (2007). Kohal RJ: Behavior of CAL72 osteoblast-like cells cultured on zirconia ceramics with different surface topographies. Clin Oral Implants Res
  17. (1999). Le Charpentier Y: Evaluation of combinations of titanium, zirconia, and alumina implants with 2 bone fillers in the dog. Int J Oral Maxillofac Implants
  18. (2004). Loaded custom-made zirconia and titanium implants show similar osseointegration: an animal experiment.
  19. (1999). Maccauro G: Zirconia as a ceramic biomaterial. Biomaterials
  20. (2008). Osseointegration and clinical success of zirconia dental implants: a systematic review.
  21. (2001). Osteoinduction, osteoconduction and osseointegration.
  22. (2003). RD: Implant materials, design, and surface topographies: their influence on osseointegration of dental implants. J Long Term Eff Med Implants
  23. (2002). Restitution of maxillary anterior aesthetics with allceramic components. Int Dent J
  24. (2004). Steinemann SG: Enhanced bone apposition to a chemically modified SLA titanium surface. J Dent Res
  25. (2003). Surface chemistry effects of topographic modification of titanium dental implant surfaces: 1. Surface analysis. Int J Oral Maxillofac Implants
  26. (1995). Zirconia posts: a new allceramic concept for nonvital abutment teeth.

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