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J Acquir Immune Defic Syndr

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Abstract

BackgroundIn 2007, 29% of HIV-infected Kenyans in need of antiretroviral therapy (ART), based on an immunologic criterion of CD4 64350 cells per microliter, were receiving ART. Since then, substantial treatment scale-up has occurred in the country. We analyzed data from the second Kenya AIDS Indicator Survey (KAIS 2012) to assess progress of treatment scale-up in Kenya.MethodsKAIS 2012 was a nationally representative survey of persons aged 18 months to 64 years that collected information on HIV status, care, and treatment. ART eligibility was defined based on 2 standards: (1) 2011 Kenya eligibility criteria for ART initiation: CD4 64350 cells per microliter or co-infection with active tuberculosis and (2) 2013 World Health Organization (WHO) eligibility criteria for ART initiation: CD4 64500 cells per microliter, co-infection with active tuberculosis, currently pregnant or breastfeeding, and infected partners in serodiscordant relationships. Blood specimens were tested for HIV antibodies and HIV-positive specimens tested for CD4 cell counts.ResultsAmong 13,720 adults and adolescents aged 15\u201364 years, 11,626 provided a blood sample, and 648 were HIV infected. Overall, 58.8% [95% confidence interval (CI): 52.0 to 65.5) were eligible for treatment using the 2011 Kenya eligibility criteria and 77.4% (95% CI: 72.4 to 82.4) using the 2013 WHO eligibility criteria. Coverage of ART was 60.5% (95% CI: 50.8 to 70.2) using the 2011 Kenya eligibility criteria and 45.9% (95% CI: 37.7 to 54.2) using the 2013 WHO eligibility criteria.ConclusionsART coverage has increased from 29% in 2007 to 61% in 2012. If Kenya adopts the 2013 WHO guidelines for ART initiation, need for ART increases by an additional 19 percentage points and current coverage decreases by an additional 15 percentage points, representing an additional 214,000 persons who will need to be reached.20142016-03-10T00:00:00ZCC999999/Intramural CDC HHS/United States24732815PMC478617

Topics: Article, AIDS Serodiagnosis, Adolescent, Adult, Age Factors, Anti-Retroviral Agents, CD4 Lymphocyte Count, Educational Status, Eligibility Determination, Female, HIV Infections, Health Knowledge, Attitudes, Practice, Health Services Accessibility, Health Surveys, Humans, Male, Marital Status, Middle Aged, Patient Acceptance of Health Care, Sex Factors, World Health Organization, Young Adult
OAI identifier: oai:cdc.stacks:cdc:38415
Provided by: CDC Stacks
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