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Influence of intracranial hemorrhage and neonatal seizures on the neurological and psychomotor development of premature infants at Hospital de Clínicas de Porto Alegre, Brazil

By Lygia Ohlweiler, Alexandre Rodrigues da Silva, Sonja Vergínia Barros, Rudimar Riesgo and Newra Tellechea Rotta

Abstract

This study compared the results of neurodevelopmental examination at 6 months' corrected age of premature infants with neonatal seizures and/or intracranial hemorrhage and normal premature infants. There was a statistically significant correlation (p=0.000007) between intracranial hemorrhage and seizures in the group of 68 premature infants seen in the neurodevelopmental outpatient service at Hospital de Clínicas de Porto Alegre, Brazil. Intracranial hemorrhage was significantly associated with multiparity (p=0.02). The neurodevelopmental examination at 6 months' corrected age revealed that patients who suffered neonatal intracranial hemorrhage and/or seizures had inappropriate muscle tone, strength and reflexes, as well as delay in head control. Conclusion: we compared the results of neurodevelopmental examinations of two groups of premature infants at 6 months' corrected age. The difference in neurological development at 6 months' corrected age was statistically significant when comparison was corrected for premature infants who had neonatal seizures and periventricular hemorrhage

Topics: neurological and psychomotor development, neonates, intracranial hemorrhage, neonatal seizures
Publisher: Academia Brasileira de Neurologia - ABNEURO
Year: 2003
OAI identifier: oai:periodicos.ibict.br.ArquivosdeNeuroPsiquiatria:oai:scielo:S0004-282X2003000600002
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