Article thumbnail
Location of Repository

Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility

By Anatoly Shmygol, Joanna Gullam, Andrew M. Blanks and Steven Thornton

Abstract

Oxytocin is a small peptide hormone with multiple sites of action in human body. It regulates a large number of reproduction-related processes in all species. Particularly important is its ability to stimulate uterine contractility. This is achieved by multiple mechanisms involving sarcoplasmic reticulum Ca2+ release and sensitization of the contractile apparatus to Ca2+. In this paper, we review the data published by us and other groups on oxytocin-induced modulation of uterine contractility. We conclude that sensitization of contractile apparatus to Ca2+ is the most relevant physiological effect of oxytocin on human myometrium

Topics: QD, RS
Publisher: Blackwell Pubishing
OAI identifier: oai:wrap.warwick.ac.uk:33388
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dx.doi.org/10.1111/j.17... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.