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The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994.

By Tom Bates, A. Antoniou, R.E.K. Marshall, Margaret Harrison and Eryl E. Bassett

Abstract

Abstract: Background: The management of esophageal carcinoma is changing but before the introduction of\ud chemotherapy and multidisciplinary teams, surgery became more selective. The aim of this study was to confirm this\ud trend and to examine survival in a total population cohort 1985-94.\ud Results: Only a quarter of 413 patients had surgery but from 1989 even fewer were operated on but there were more longterm\ud survivors: 1/51 v. 7/58 (p<0.05). Operative mortality fell from 12% to 6.9 % in the later period (N.S.) and survival\ud post surgery was marginally improved, 15 v. 11 months p = 0.0502. The five year survival rate doubled from 7.8% to\ud 17.2%.\ud Conclusion: Few studies of esophageal cancer include all cases in a defined population. This carries a very poor prognosis\ud but the present cohort shows a slight improvement with more selective surgery and this may serve as a benchmark against\ud which modern multidisciplinary management might be compared.\ud Keywords: Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis

Topics: RD, R
Publisher: Bentham Open
Year: 2008
OAI identifier: oai:kar.kent.ac.uk:23626
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