Article thumbnail
Location of Repository

Stereoselectivity in amidyl radical cyclisations. Acyl mode cyclisations.

By 

Abstract

Amidyl radicals generated from tributylstannane mediated homolysis of O-benzoyl hydroxamic acid derivatives undergo 5-exo cyclisation to give mixtures of cis and trans pyrrolidinones. While the steric nature of the nitrogen substituents investigated had little effect on the diastereoselectivity of the process they did effect the relative rate of the cyclisation reactions. The major products could be predicted by application of the "Beckwith rule". (C) 1998 Elsevier Science Ltd. All rights reserved

Topics: QD
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
OAI identifier: oai:wrap.warwick.ac.uk:15517
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.